Cardiovascular, Immune And Liver Protection -- Garlic Extract
- Mar 23, 2018 -

12 weeks of 2018


Garlic is a condiment and a herbal medicine. It has its medicinal record in every culture and history. The earliest records of garlic treatment can be traced back to the Zoroastrian culture in the sixth Century B.C. Sumerians, ancient Egyptians and Greeks also used the treatment of garlic. In addition, Chinese medicine and Ayurveda in India also praised garlic's use and had penetrated into its everyday traditions.

Modern science has verified the application of garlic in tradition. Pharmacological studies suggest that garlic has antioxidant, increased nitric oxide content, and inhibits angiotensin-converting enzyme (ACE) and other characteristics. The ability of garlic to reduce inflammation is accomplished by various enzymes, including cyclooxygenase (COX) and lipoxygenase (LOX), and the total switch nuclear transcription factor K B (NF- kappa B), which controls the occurrence of inflammation at atomic level.

Clinical studies suggest that garlic can maintain normal platelet aggregation, reduce lipid peroxidation, and support healthy blood lipid levels. These mechanisms enable garlic to support cardiovascular function, immune health and many other health problems. Recent research on garlic has focused on reducing coronary plaque, immune health, liver function and weight management.

1. Coronary atherosclerotic plaque

Coronary plaque is a significant risk factor for heart disease. Plaque can be divided into calcified patches and non calcified patches (soft patches) according to their characteristics. Studies suggest that simultaneous occurrence of non calcified plaques and calcified plaques can better predict the risk of coronary heart disease.

Early studies have demonstrated the effect of garlic on calcified plaques. The aim of the new study is to evaluate the effect of garlic juice on reducing non calcified artery plaques. The study, carried out by Suguru Matusumoto at the University of California at Los Angeles medical center, included 55 patients with metabolic syndrome, who were asked to use an old garlic extract supplement (2400 mg / day) or a placebo for one year. Before the beginning of the study, the assessment included cardiac angiography (CCTA). The study used Wakunaga's Kyolic garlic extract. The study found that compared with the control group, the old garlic extract could significantly reduce the rate of low density plaque, and the low density plaque was considered to be a part of the non calcified plaque. Therefore, researchers believe that garlic extract can promote cardiovascular health by reducing these plaques.

2. Support liver health

Garlic is generally not associated with liver health. Recent studies have shown that garlic extract can actually support liver health.

Researchers from the Catholic University of Korea conducted a randomized trial of 75 adults with mild liver dysfunction but not diagnosed with liver disease. Participants were randomly fed garlic extract or placebo, 2 bags a day for 12 weeks. Before the start of the study, all the participants in the study examined the level of serum gamma- transferase (GGT).

At the end of the 12 week, the researchers re evaluated the GGT content and the content of alanine aminotransferase (ALT) in the participants. The results showed that the ALT and GGT levels in the garlic group improved in comparison with the placebo group, suggesting that garlic supplementation helped to promote liver health in patients with mild liver dysfunction. The researchers also say changes in liver enzymes may also indicate that fermented garlic extract may contribute to more severe liver dysfunction.

3. Promote immune function

Several compounds in garlic can enhance immune defense ability by interacting with the immune system.

A recent study by the Susan Percival (Susan Percival) leading research team at the University of Florida assessed the effects of the old garlic extract on the proliferation, activation and inflammation of immune cells. In this double - blind placebo-controlled study, 120 healthy adults were supplemented with 2.56 grams of old garlic extract or placebo for 90 days in the season of influenza and influenza epidemic. At the beginning of the 90 day intervention study, the researchers separated the peripheral blood mononuclear cells (an immune cell) and assessed the function of T- cells and natural killer (NK) cells in forty-fifth and ninetieth.

Studies suggest that garlic extract can significantly improve the proliferation of T- cells and NK cells, and reduce the severity of colds and influenza (not the frequency of cold). The garlic extract can improve the symptoms, and the time for people to take cold drinks with garlic extract is shortened. This indicates that garlic preparations have multiple benefits to immune health and support their preventive benefits to healthy adults.

4. It helps to control weight

Previous animal studies have found that garlic may help reduce weight. However, it is not clear whether this phenomenon occurs in humans.

Not long ago, a study conducted in Iran was conducted to assess the effects of garlic on body weight and body composition parameters in patients with nonalcoholic fatty liver disease (NAFLD). Because overweight is a risk factor for the development of NAFLD, weight loss can also promote liver health.

In this study, 110 participants were recruited from the center for metabolic liver disease at the University of Isfahan in Iran, randomly divided into two groups, one group of 400 mg of garlic powder (1.5 milligram of allicin), two times a day, and the other for 15 weeks. The two groups were monitored for diet and exercise and received basic dietary and exercise advice. During the experiment, the participants assessed the body composition parameters of all participants.

The results showed that the average weight of garlic group decreased by 2.59% compared with the beginning, while that of placebo group decreased by 0.75%. The body fat of the garlic supplement group decreased by 2.91%, while the placebo group decreased by 0.42%. These results indicate that garlic supplements can be a useful supplement to the weight management lifestyle of overweight people.

March 23, 2018